Drosophila melanogasterGenAge entry for AhcyL2 (Drosophila melanogaster)

Gene information (ID: 2085)

Symbol
AhcyL2
Name
Adenosylhomocysteinase like 2
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Downregulation of two out of three of Drosophila homologs of AHCY significantly extended life span in adult males and females, median lifespan was 21% higher when Ahcy89E was downregulated. Intestine specific downregulation of Ahcy89E resulted in increased lifespan and health span.
% change in avg or median lifespan
Median lifespan is 21% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Rattus norvegicus
    Ahcyl1

    External links

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    Entrez Gene
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    Internet
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