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BIBLIO ID Title Impact Link
0001A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)1PubMed
0002Is the Laron mouse an accurate model of Laron syndrome?1PubMed
0003Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span4PubMed
0004Assessment of growth parameters and life span of GHR/BP gene-disrupted mice1PubMed
0005Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production2PubMed
0006The p66shc adaptor protein controls oxidative stress response and life span in mammals2PubMed
0007Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway2PubMed
0008A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis2PubMed
0009Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet1PubMed
0010Dwarf mice and the ageing process1PubMed
0011p53 mutant mice that display early ageing-associated phenotypes1PubMed
0012Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing2PubMed
0013Transgenic mice overexpressing urokinase-type plasminogen activator in the brain exhibit reduced food consumption, body weight and size, and increased longevity1PubMed
0014Premature aging in mice deficient in DNA repair and transcription2PubMed
0015The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH2PubMed
0016Positional cloning of the Werner's syndrome gene1PubMed
0017Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome1PubMed
0018IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice2PubMed
0019Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span1PubMed
0020Mutation of the mouse klotho gene leads to a syndrome resembling ageing1PubMed


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