Caenorhabditis elegans in DrugAge

Summary

Top life-extending compounds for Caenorhabditis elegans

Compound NameAssaysAvg Lifespan Change (%)Maximum Lifespan Change (%)
Ethanol2155.2
D-glutamate3114
N-butanol1108.1
N-propanol195.5
Hydrogen Sulphide174
Caffeine2465
Thioflavin T160 78
Carbonylcyanide-3-chlorophenylhydrazone160
Bacitracin158.5 74
Paraquat158 48
Metformin1157.3 0
Rifampicin1056.1
EUK-134754
Taxifolin151
Resveratrol1450.8 29.2
N-acetylglucosamine150
Acetaminophen148.6 59
Alpha-ketoglutarate647.9
Shengmai yin147.3
Trimethadione747 57
Baicalein245 52
Loxapine succinate143
(R)-2-hydroxyglutarate142.9
Psora-4142
Ciclopirox olamine141 52
Electrolyzed reduced water741 13.8
Whole apple extract139 25
Acacetin 7-O-alpha-l-rhamnopyranosyl (1_2) beta-D-xylopyranoside 539
Curcumin239
Protocatechuic acid238.9 40
Huanshao dan138.3
Octoclothepin maleate138
Amperozide hydrochloride138
EUK-81938
Pergolide methanesulfonate137
Crude BB extract (Vaccinium angustifolium)137
Proanthocycanidin136.6
Doxycycline536.5
Lithium Chloride336 0
Valproic acid135 42
N-(2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl)-3-methoxybenzamide135
Ethosuximide535 37
Reishi polysaccharide135
Ampicillin 134
Dihydroergocristine methanesulfonate134
LY-367,265134
Sulfamethoxazole334 0
Royalactin333.9
LY-165,163133
Chlorprothixene hydrochloride133
Summary Total Assays: 659Max: 155.2 Max: 78

Results

Compound Name Avg Lifespan change (%) Max Lifespan change (%) Synonyms Strain Dosage Gender Significance
Selected Lifespan Change:
Compound Name Avg Lifespan change (%) Max Lifespan change (%) Synonyms Strain Dosage Gender Significance Reference

Species in other databases

GenAge
Genes have been associated with ageing in this organism
GenDR