Trimethadione in DrugAge

Summary

SpeciesAssaysAvg Lifespan Change (%)Maximum Lifespan Change (%)
Caenorhabditis elegans747 57
Summary Total Assays: 7 Max: 47 Max: 57

Results for Trimethadione

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance

Selected Lifespan Change:

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance Reference

References

Primary References
Evason, K et al. (2005) Anticonvulsant medications extend worm life-span. Science 307(5707)258-262 PubMed
Shibamura, A et al. (2009) A method for oral administration of hydrophilic substances to Caenorhabditis elegans: Effects of oral supplementation with antioxidants on the nematode lifespan. Mech. Ageing Dev. 130(9)652-655 PubMed

DGIdb human gene-drug interactions for Trimethadione

Entrez Gene Symbol Gene Name Interaction Source Interaction Type GenAge Interactions

Stitch DB human protein-drug interactions for Trimethadione

The data below is based on a Stitch DB API call for human protein-drug interactions for Trimethadione

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above.

Trimethadione

Displayed below are the associated biological networks for each of the top 20 direct Trimethadione protein interactors.

Ensembl Id StringDB Id