Spermidine in DrugAge

Summary

SpeciesAssaysAvg Lifespan Change (%)Maximum Lifespan Change (%)
Saccharomyces cerevisiae1233
Drosophila melanogaster130
Caenorhabditis elegans115
Summary Total Assays: 3 Max: 233 Max:

Results for Spermidine

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance

Selected Lifespan Change:

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance Reference

References

Primary References
Eisenberg, T et al. (2009) Induction of autophagy by spermidine promotes longevity. Nat. Cell Biol. 11(11)1305-1314 PubMed

DGIdb human gene-drug interactions for Spermidine

Entrez Gene Symbol Gene Name Interaction Source Interaction Type GenAge Interactions

Stitch DB human protein-drug interactions for Spermidine

The data below is based on a Stitch DB API call for human protein-drug interactions for Spermidine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above.

Spermidine

Displayed below are the associated biological networks for each of the top 20 direct Spermidine protein interactors.

Ensembl Id StringDB Id