Quercetin in DrugAge

Summary

SpeciesAssaysAvg Lifespan Change (%)Maximum Lifespan Change (%)
Caenorhabditis elegans1919 29
Summary Total Assays: 19 Max: 19 Max: 29

Results for Quercetin

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance

Selected Lifespan Change:

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance Reference

References

Primary References
Kampkötter, A et al. (2008) Increase of stress resistance and lifespan of Caenorhabditis elegans by quercetin. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 149(2)314-323 PubMed
Saul, N et al. (2008) Quercetin-mediated longevity in Caenorhabditis elegans: is DAF-16 involved? Mech. Ageing Dev. 129(10)611-613 PubMed
Pietsch, K et al. (2009) Quercetin mediated lifespan extension in Caenorhabditis elegans is modulated by age-1, daf-2, sek-1 and unc-43. Biogerontology 10(5)565-578 PubMed
Xue, YL et al. (2011) Isolation and Caenorhabditis elegans lifespan assay of flavonoids from onion. J. Agric. Food Chem. 59(11)5927-5934 PubMed
Pietsch, K et al. (2012) Meta-Analysis of Global Transcriptomics Suggests that Conserved Genetic Pathways are Responsible for Quercetin and Tannic Acid Mediated Longevity in C. elegans. Front Genet 3()48 PubMed

DGIdb human gene-drug interactions for Quercetin

Entrez Gene Symbol Gene Name Interaction Source Interaction Type GenAge Interactions

Stitch DB human protein-drug interactions for Quercetin

The data below is based on a Stitch DB API call for human protein-drug interactions for Quercetin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above.

Quercetin

Displayed below are the associated biological networks for each of the top 20 direct Quercetin protein interactors.

Ensembl Id StringDB Id