Minocycline in DrugAge

Summary

SpeciesAssaysAvg Lifespan Change (%)Maximum Lifespan Change (%)
Drosophila melanogaster463 66
Summary Total Assays: 4 Max: 63 Max: 66

Results for Minocycline

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance

Selected Lifespan Change:

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance Reference

References

Primary References
Bonilla, E et al. (2012) Minocycline increases the life span and motor activity and decreases lipid peroxidation in manganese treated Drosophila melanogaster. Toxicology 294(1)50-53 PubMed
Oxenkrug, G et al. (2012) Minocycline effect on life and health span of Drosophila melanogaster. Aging Dis 3(5)352-359 PubMed
Mora, M et al. (2013) Minocycline, but not ascorbic acid, increases motor activity and extends the life span of Drosophila melanogaster. Invest Clin 54(2)161-170 PubMed

DGIdb human gene-drug interactions for Minocycline

Entrez Gene Symbol Gene Name Interaction Source Interaction Type GenAge Interactions

Stitch DB human protein-drug interactions for Minocycline

The data below is based on a Stitch DB API call for human protein-drug interactions for Minocycline

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above.

Minocycline

Displayed below are the associated biological networks for each of the top 20 direct Minocycline protein interactors.

Ensembl Id StringDB Id