Lithocholic acid in DrugAge

Summary

SpeciesAssaysAvg Lifespan Change (%)Maximum Lifespan Change (%)
Saccharomyces cerevisiae1100
Summary Total Assays: 1 Max: 100 Max:

Results for Lithocholic acid

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance

Selected Lifespan Change:

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance Reference

References

Primary References
Goldberg, AA et al. (2010) Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes. Aging (Albany NY) 2(7)393-414 PubMed

DGIdb human gene-drug interactions for Lithocholic acid

Entrez Gene Symbol Gene Name Interaction Source Interaction Type GenAge Interactions

Stitch DB human protein-drug interactions for Lithocholic acid

The data below is based on a Stitch DB API call for human protein-drug interactions for Lithocholic acid

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above.

Lithocholic acid

Displayed below are the associated biological networks for each of the top 20 direct Lithocholic acid protein interactors.

Ensembl Id StringDB Id