Glycerol in DrugAge

Summary

SpeciesAssaysAvg Lifespan Change (%)Maximum Lifespan Change (%)
Brachionus manjavacas151
Caenorhabditis elegans421
Summary Total Assays: 5 Max: 51 Max:

Results for Glycerol

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance

Selected Lifespan Change:

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance Reference

References

Primary References
Lee, SJ et al. (2009) Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression. Cell Metab. 10(5)379-391 PubMed
Snell, TW and Johnston, RK (2014) Glycerol extends lifespan of Brachionus manjavacas (Rotifera) and protects against stressors. Exp. Gerontol. 57()47-56 PubMed
Edwards, C et al. (2015) Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet. 16()8 PubMed

DGIdb human gene-drug interactions for Glycerol

Entrez Gene Symbol Gene Name Interaction Source Interaction Type GenAge Interactions

Stitch DB human protein-drug interactions for Glycerol

The data below is based on a Stitch DB API call for human protein-drug interactions for Glycerol

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above.

Glycerol

Displayed below are the associated biological networks for each of the top 20 direct Glycerol protein interactors.

Ensembl Id StringDB Id