Baicalein in DrugAge

Summary

SpeciesAssaysAvg Lifespan Change (%)Maximum Lifespan Change (%)
Caenorhabditis elegans245 52
Summary Total Assays: 2 Max: 45 Max: 52

Results for Baicalein

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance

Selected Lifespan Change:

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance Reference

References

Primary References
Lublin, A et al. (2011) FDA-approved drugs that protect mammalian neurons from glucose toxicity slow aging dependent on cbp and protect against proteotoxicity. PLoS ONE 6(11)e27762 PubMed
Havermann, S et al. (2013) Molecular effects of baicalein in Hct116 cells and Caenorhabditis elegans : activation of the Nrf2 signaling pathway and prolongation of lifespan. J. Agric. Food Chem. 61(9)2158-2164 PubMed

DGIdb human gene-drug interactions for Baicalein

Entrez Gene Symbol Gene Name Interaction Source Interaction Type GenAge Interactions

Stitch DB human protein-drug interactions for Baicalein

The data below is based on a Stitch DB API call for human protein-drug interactions for Baicalein

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above.

Baicalein

Displayed below are the associated biological networks for each of the top 20 direct Baicalein protein interactors.

Ensembl Id StringDB Id