Aspirin in DrugAge

Summary

SpeciesAssaysAvg Lifespan Change (%)Maximum Lifespan Change (%)
Acheta domesticus6134
Caenorhabditis elegans323
Mus musculus18 0
Summary Total Assays: 10 Max: 134 Max: 0

Results for Aspirin

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance

Selected Lifespan Change:

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance Reference

References

Primary References
Strong, R et al. (2008) Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice. Aging Cell 7(5)641-650 PubMed
Ayyadevara, S et al. (2013) Aspirin inhibits oxidant stress, reduces age-associated functional declines, and extends lifespan of Caenorhabditis elegans. Antioxid. Redox Signal. 18(5)481-490 PubMed
Wan, QL et al. (2013) Aspirin extends the lifespan of Caenorhabditis elegans via AMPK and DAF-16/FOXO in dietary restriction pathway. Exp. Gerontol. 48(5)499-506 PubMed
Hans, H et al. (2015) Impacts of metformin and aspirin on life history features and longevity of crickets: trade-offs versus cost-free life extension? Age (Dordr) 37(2)31 PubMed

DGIdb human gene-drug interactions for Aspirin

Entrez Gene Symbol Gene Name Interaction Source Interaction Type GenAge Interactions

Stitch DB human protein-drug interactions for Aspirin

The data below is based on a Stitch DB API call for human protein-drug interactions for Aspirin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above.

Aspirin

Displayed below are the associated biological networks for each of the top 20 direct Aspirin protein interactors.

Ensembl Id StringDB Id