Ascorbic acid in DrugAge

Summary

SpeciesAssaysAvg Lifespan Change (%)Maximum Lifespan Change (%)
Paramecium tetraurelia112.1 6.7
Caenorhabditis elegans20 50
Summary Total Assays: 3 Max: 12.1 Max: 50

Results for Ascorbic acid

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance

Selected Lifespan Change:

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance Reference

References

Primary References
Harrington, LA and Harley, CB (1988) Effect of vitamin E on lifespan and reproduction in Caenorhabditis elegans. Mech. Ageing Dev. 43(1)71-78 PubMed
Thomas, JN and Smith-Sonneborn, J (1997) Supplemental melatonin increases clonal lifespan in the protozoan Paramecium tetraurelia. J. Pineal Res. 23(3)123-130 PubMed
Shibamura, A et al. (2009) A method for oral administration of hydrophilic substances to Caenorhabditis elegans: Effects of oral supplementation with antioxidants on the nematode lifespan. Mech. Ageing Dev. 130(9)652-655 PubMed

DGIdb human gene-drug interactions for Ascorbic acid

Entrez Gene Symbol Gene Name Interaction Source Interaction Type GenAge Interactions

Stitch DB human protein-drug interactions for Ascorbic acid

The data below is based on a Stitch DB API call for human protein-drug interactions for Ascorbic acid

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above.

Ascorbic acid

Displayed below are the associated biological networks for each of the top 20 direct Ascorbic acid protein interactors.

Ensembl Id StringDB Id