(R)-2-hydroxyglutarate in DrugAge

Summary

SpeciesAssaysAvg Lifespan Change (%)Maximum Lifespan Change (%)
Caenorhabditis elegans142.9
Summary Total Assays: 1 Max: 42.9 Max:

Results for (R)-2-hydroxyglutarate

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance

Selected Lifespan Change:

Species Avg Lifespan change (%) Max Lifespan change (%) Strain Dosage Gender Significance Reference

References

Primary References
Fu, X et al. (2015) 2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling. Cell Metab. 22(3)508-515 PubMed

DGIdb human gene-drug interactions for (R)-2-hydroxyglutarate

Entrez Gene Symbol Gene Name Interaction Source Interaction Type GenAge Interactions

Stitch DB human protein-drug interactions for (R)-2-hydroxyglutarate

The data below is based on a Stitch DB API call for human protein-drug interactions for (R)-2-hydroxyglutarate

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above.

(R)-2-hydroxyglutarate

Displayed below are the associated biological networks for each of the top 20 direct (R)-2-hydroxyglutarate protein interactors.

Ensembl Id StringDB Id