GenDR Dietary Restriction Gene Manipulation: ISW2
Gene Information (Entrez Gene ID: 854480)
Potential relevance to dietary restriction and ageing
Under normal conditions, deletion of ISW2 in yeast extends replicative lifespan by 24%. Lifespan is also extended by limiting glucose concentrations in the diet to either 0.5% or 0.05%, however, these CR conditions are not able to extend lifespan when ISW2 is deleted, instead shortening lifespan.
In other databases
- GenAge model organism genes
- This gene is present as ISW2
- Caenorhabditis elegans