Drosophila melanogaster GenDR Dietary Restriction Gene Manipulation: CG4389

Gene Information (Entrez Gene ID: 34276)

Symbol
CG4389
Aliases
BcDNA:GH12558 CG 4389 CG4389 Dmel\CG4389
Name
CG4389 gene product from transcript CG4389-RA
Organism
Drosophila melanogaster (AnAge)
Entrez Gene ID
34276

Potential relevance to dietary restriction and ageing

Observations

Muscle-specific RNAi knockdown of CG489 which reduces its mRNA levels by 25-35%, significantly reduces the DR-dependent lifespan extension. CG4389 RNAi animals exhibit only 20% increase while controls display a lifespan increase of 123% upon DR [2597].

References

    Homologs

    Caenorhabditis elegans
    ech-1.1
    Caenorhabditis elegans
    ech-1.2
    Danio rerio
    hadhab
    Danio rerio
    hadhaa
    Homo sapiens
    HADHA
    Mus musculus
    Hadha
    Rattus norvegicus
    Hadha

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    ID 34276
    Homologues
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    UniProt
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    Internet
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