Caenorhabditis elegans GenDR Dietary Restriction Gene Manipulation: ucp2

Gene Information (Entrez Gene ID: 555812)

Symbol
ucp2
Aliases
cb74
Name
uncoupling protein 2
Organism
Caenorhabditis elegans (AnAge)
Entrez Gene ID
555812

Potential relevance to dietary restriction and ageing

Observations

Overexpression of zebrafish's ucp2 in nematode increases mean, median, and maximum lifespan by 42, 40, and 26%, which is non-additive with solid DR [2588].

References

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as UCP2
    • A homolog of this gene for Mus musculus is present as Ucp2
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as UCP2
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as UCP2

    Homologs

    Homo sapiens
    UCP2
    Mus musculus
    Ucp2
    Rattus norvegicus
    Ucp2
    Saccharomyces cerevisiae
    DIC1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    ID 555812
    Homologues
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    UniProt
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    Internet
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