GenDR Dietary Restriction Gene Manipulation: GUP1
Gene Information (Entrez Gene ID: 852796)
Potential relevance to dietary restriction and ageing
GUP1 deletion extends mean and maximum replicative lifespan by 32 and 30%, respectively, as well as chronological lifespan. DR-induced maximal replicative lifespan extension is not further increased by GUP1 deletion, while gup1 mutant displayed slightly longer chronological lifespan under DR .
No homologs found