GenDR Dietary Restriction Gene Manipulation: MSN2
Gene Information (Entrez Gene ID: 855053)
- Multicopy suppressor of SNF1 mutation 2
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
Potential relevance to dietary restriction and ageing
Deletion of MSN2 and MSN4 extends replicative lifespan . Deletion of MSN2 and MSN4 does not significantly decrease chronological lifespan under ad libitum, but attenuates chronological lifespan extension by water starvation and 0.5% glucose restriction . msn2 msn4 has no effect on replicative lifespan in PSY316, and does not prevent lifespan extension by DR .