Cell Senescence-associated Genes

Found 279 results. Showing results 161 to 180.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
NOTCH3KnockdownGlioma, Fibroblast, Melanoma, Foreskin fibroblast, Breast cancerBJ, LF1, WS1, MDA-MB-231, A375P, T98GYesStress-inducedPromotes
NOX4Overexpression, KnockdownLung fibroblast, Breast epithelialMCF-12A, TIG-3NoReplicativePromotes
NR2E1KnockoutProstate epithelial, Lung fibroblast, Neural StemIMR-90, WI-38NoOncogene-inducedUnclear
NTN4Overexpression, KnockdownGliomaU-251MG, U-U118MG, T98G, U-87MGYesStress-inducedInhibits
NUAK1Overexpression, KnockoutLung fibroblastWI-38NoReplicativePromotes
OTX2OverexpressionMedulloblastomaMED8A, UW228-2, D458, D556, D283, DAOY, D425, D341YesReplicativePromotes
P3H1KnockdownLung fibroblastIMR-90NoStress-induced, ReplicativeInhibits
PAK4OverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
PATZ1Knockdown, OverexpressionUmbilical vein endothelialPrimary cellNoReplicativeInhibits
PBRM1KnockdownForeskin fibroblastBJNoReplicativePromotes
PCGF2Knockout, OverexpressionForeskin fibroblast, Lung fibroblastMRC-5, WI-38, BJNoReplicativePromotes
PDCD10KnockoutCoronary artery endothelial, Lung fibroblastPrimary cell, IMR-90NoReplicative, Oncogene-inducedPromotes
PDIK1LOverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
PDPK1OverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
PDZD2OverexpressionBreast cancer, Prostate cancer, Liver cancerDU145YesReplicativePromotes
PEBP1Overexpression, KnockdownProstate cancer, Colon cancer, Lung cancer, Gastric cancerA549, MKN45, PC-3, HCT116YesStress-inducedPromotes
PEX19OverexpressionOsteosarcomaU2OSYesStress-inducedPromotes
PIAS4OverexpressionLung fibroblastWI-38NoReplicativePromotes
PIK3C2AKnockdownEmbryonic kidney, Retinal pigment epithelialhTERT-RPE1, HEK293TYesReplicativeUnclear
PIK3R5OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes