Cell Senescence-associated Genes

Found 279 results. Showing results 161 to 180.

Show: Sort: First Previous  of 14 Next Last 
Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
NOTCH3KnockdownBreast cancer, Fibroblast, Foreskin fibroblast, Glioma, MelanomaA375P, BJ, LF1, MDA-MB-231, T98G, WS1YesStress-inducedPromotes
NOX4Knockdown, OverexpressionBreast epithelial, Lung fibroblastMCF-12A, TIG-3NoReplicativePromotes
NR2E1KnockoutLung fibroblast, Neural Stem, Prostate epithelialIMR-90, WI-38NoOncogene-inducedUnclear
NTN4Knockdown, OverexpressionGliomaT98G, U-251MG, U-87MG, U-U118MGYesStress-inducedInhibits
NUAK1Knockout, OverexpressionLung fibroblastWI-38NoReplicativePromotes
OTX2OverexpressionMedulloblastomaD283, D341, D425, D458, D556, DAOY, MED8A, UW228-2YesReplicativePromotes
P3H1KnockdownLung fibroblastIMR-90NoReplicative, Stress-inducedInhibits
PAK4OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
PATZ1Knockdown, OverexpressionUmbilical vein endothelialPrimary cellNoReplicativeInhibits
PBRM1KnockdownForeskin fibroblastBJNoReplicativePromotes
PCGF2Knockout, OverexpressionForeskin fibroblast, Lung fibroblastBJ, MRC-5, WI-38NoReplicativePromotes
PDCD10KnockoutCoronary artery endothelial, Lung fibroblastIMR-90, Primary cellNoOncogene-induced, ReplicativePromotes
PDIK1LOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
PDPK1OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
PDZD2OverexpressionBreast cancer, Liver cancer, Prostate cancerDU145YesReplicativePromotes
PEBP1Knockdown, OverexpressionColon cancer, Gastric cancer, Lung cancer, Prostate cancerA549, HCT116, MKN45, PC-3YesStress-inducedPromotes
PEX19OverexpressionOsteosarcomaU2OSYesStress-inducedPromotes
PIAS4OverexpressionLung fibroblastWI-38NoReplicativePromotes
PIK3C2AKnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeUnclear
PIK3R5OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes