Cell Senescence-associated Genes

Found 279 results. Showing results 101 to 120.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
IL1AKnockoutUmbilical vein endothelialPrimary cellNoReplicativePromotes
IL8OverexpressionForeskin fibroblast, Lung fibroblastBJ, IMR-90, WI-38NoReplicativePromotes
ING1OverexpressionForeskin fibroblastHs68NoReplicativePromotes
ING2Knockout, OverexpressionLung fibroblastMRC-5NoReplicativePromotes
IRF3OverexpressionForeskin fibroblastBJNoReplicativePromotes
IRF5OverexpressionLi Fraumeni syndrome fibroblastMDAH041YesReplicativePromotes
IRF7OverexpressionLi Fraumeni syndrome fibroblastMDAH041YesReplicativePromotes
ITGB4KnockdownUmbilical vein endothelialPrimary cellNoReplicativePromotes
ITPK1OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
ITPKBOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
ITSN2Knockdown, OverexpressionForeskin fibroblast, Lung fibroblastHs68, WI-38NoStress-inducedPromotes
KCNJ12KnockoutBreast cancer, Gastric cancer, Prostate cancerDU145, LNCaP, MCF-7, MKN74, PC-3, SK-BR3, SNU-484, SNU-638, SNU-668, T47DYesStress-inducedInhibits
KDM4AKnockdownLung cancerA549YesReplicativeUnclear
KDM5BKnockdownColon cancerColo201, DLD1, HCT116YesReplicativeInhibits
KIAA1524KnockdownGastric cancerAGS, BGC-823, HGC-27, KATO-IIIYesReplicativeInhibits
KLKnockdownLung fibroblastMRC-5, WI-38NoReplicativeInhibits
KSR2KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeUnclear
LATS1KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
LEO1OverexpressionLung fibroblast2BSNoReplicativeUnclear
LGALS3KnockdownGastric cancerAGS, KATO-III, MKN28, SNU-1, SNU-16, SNU-216, SNU-5, SNU-601, SNU-638, SNU-668, SNU-719, YCC-2YesReplicativeInhibits