Cell Senescence-associated Genes

Found 279 results. Showing results 101 to 120.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
IL1AKnockoutUmbilical vein endothelialPrimary cellNoReplicativePromotes
IL8OverexpressionForeskin fibroblast, Lung fibroblastIMR-90, BJ, WI-38NoReplicativePromotes
ING1OverexpressionForeskin fibroblastHs68NoReplicativePromotes
ING2Overexpression, KnockoutLung fibroblastMRC-5NoReplicativePromotes
IRF3OverexpressionForeskin fibroblastBJNoReplicativePromotes
IRF5OverexpressionLi Fraumeni syndrome fibroblastMDAH041YesReplicativePromotes
IRF7OverexpressionLi Fraumeni syndrome fibroblastMDAH041YesReplicativePromotes
ITGB4KnockdownUmbilical vein endothelialPrimary cellNoReplicativePromotes
ITPK1OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
ITPKBOverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
ITSN2Knockdown, OverexpressionForeskin fibroblast, Lung fibroblastHs68, WI-38NoStress-inducedPromotes
KCNJ12KnockoutProstate cancer, Breast cancer, Gastric cancerPC-3, DU145, LNCaP, MKN74, SNU-484, SNU-638, SNU-668, MCF-7, SK-BR3, T47DYesStress-inducedInhibits
KDM4AKnockdownLung cancerA549YesReplicativeUnclear
KDM5BKnockdownColon cancerHCT116, DLD1, Colo201YesReplicativeInhibits
KIAA1524KnockdownGastric cancerAGS, HGC-27, KATO-III, BGC-823YesReplicativeInhibits
KLKnockdownLung fibroblastMRC-5, WI-38NoReplicativeInhibits
KSR2KnockdownEmbryonic kidney, Retinal pigment epithelialhTERT-RPE1, HEK293TYesReplicativeUnclear
LATS1KnockdownEmbryonic kidney, Retinal pigment epithelialhTERT-RPE1, HEK293TYesReplicativeInhibits
LEO1OverexpressionLung fibroblast2BSNoReplicativeUnclear
LGALS3KnockdownGastric cancerAGS, MKN28, YCC-2, KATO-III, SNU-1, SNU-5, SNU-16, SNU-216, SNU-601, SNU-638, SNU-668, SNU-719YesReplicativeInhibits