Cell Senescence-associated Genes

Found 279 results. Showing results 41 to 60.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
CDKN2AIPOverexpressionLung fibroblastTIG-1, MRC-5NoReplicativePromotes
CDKN2BOverexpressionGlioblastomaU-251MG, U-373MG, T98GYesReplicativePromotes
CEBPBOverexpression, KnockdownProstate cancerLNCaPYesStress-inducedPromotes
CENPAKnockdownLung fibroblastTIG-3NoReplicativeInhibits
CHEK1KnockoutColon cancerHCT116YesStress-inducedPromotes
CKBOverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
CPEB1Overexpression, KnockoutLung fibroblast, Foreskin fibroblastPrimary cell, WI-38NoReplicativePromotes
CSNK1A1KnockdownEmbryonic kidney, Retinal pigment epithelialhTERT-RPE1, HEK293TYesReplicativeInhibits
CSNK2A1KnockdownLung fibroblastIMR-90NoReplicativeInhibits
CTNNAL1KnockdownLung cancer, Squamous carcinomaOC2, A549YesReplicativeInhibits
CXCL1OverexpressionOvarian fibroblastGro-1NoOncogene-inducedPromotes
CYR61OverexpressionLung fibroblast, Foreskin fibroblastBJ, IMR-90NoReplicativePromotes
DDB2KnockoutLung fibroblastIMR-90NoOncogene-inducedPromotes
DEKOverexpressionForeskin keratinocytePrimary cellNoReplicativeInhibits
DGCR8KnockdownLung fibroblastIMR-90NoReplicativeInhibits
DHCR24MutationLung fibroblastWI-38NoOncogene-inducedPromotes
DHX9KnockdownLung fibroblastMRC-5NoReplicativeInhibits
DLX2OverexpressionForeskin fibroblast, Lung fibroblastBJ, IMR-90NoReplicativeInhibits
DPY30KnockoutLung fibroblastIMR-90NoReplicativeInhibits
DUSP16KnockdownEmbryonic kidney, Liver cancerHepG2, PLC/PRF/5, HEK293FTYesReplicativeInhibits