Cell Senescence-associated Genes

Found 279 results. Showing results 21 to 40.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
BLVRAKnockdownFibroblastPrimary cellNoStress-inducedInhibits
BMI1Knockout, OverexpressionForeskin fibroblast, Lung fibroblast, Skin fibroblastWI-38, BJ, 82-6NoReplicativeInhibits
BRAFOverexpressionForeskin fibroblast, MelanocytePrimary cell, BJNoOncogene-inducedPromotes
BRCA1MutationBreast cancerHBL100, MCF-7, HCC1937YesStress-inducedInhibits
BRD7KnockdownForeskin fibroblastBJNoReplicativePromotes
BTG3KnockdownLung fibroblastIMR-90, WI-38NoReplicativeInhibits
C11orf31KnockdownLung fibroblastMRC-5NoReplicativeInhibits
CAV1KnockdownFibroblastPrimary cellNoReplicativePromotes
CBX7Overexpression, KnockdownLung fibroblast, KeratinocyteWI-38, Primary cellNoReplicativeInhibits
CBX8OverexpressionFibroblastTIG-3NoReplicativeInhibits
CCND1OverexpressionFibroblastWI-38, Hs68NoReplicativePromotes
CDK1KnockdownRetinal pigment epithelial, Embryonic kidneyhTERT-RPE1, HEK293TYesReplicativeInhibits
CDK18OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
CDK2AP1KnockdownDermal fibroblastPrimary cellNoReplicativeInhibits
CDK4OverexpressionForeskin fibroblastBJNoReplicativeInhibits
CDK6OverexpressionForeskin fibroblastBJNoReplicativeInhibits
CDKN1AKnockoutFibroblastLF1NoReplicativePromotes
CDKN1BOverexpressionLung fibroblastTIG-3NoReplicativePromotes
CDKN1COverexpressionLiver cancerHepG2, SNU-398YesReplicativePromotes
CDKN2AOverexpressionLung fibroblastTIG-3NoReplicativePromotes