Cell Senescence-associated Genes

Found 279 results. Showing results 261 to 279.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
TRPM8KnockdownPancreatic cancerBxPC-3, PANC-1YesReplicativeInhibits
TXNKnockdownForeskin fibroblastBJ, BJE-LTNoReplicativeInhibits
TXNIPOverexpression, KnockoutLung fibroblast2BSNoOncogene-induced, ReplicativePromotes
TYK2OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
UBTD1OverexpressionProstate cancer, Gastric cancer, Colorectal cancer, Gastric epithelial, Lung fibroblast, Breast cancerGES-1, MKN28, KATO-III, SNU-1, SNU-16, MKN45, NCI-N87, SGC-7901, AGS, MCF-7, LoVo, PC-3, MRC-5YesReplicative, Stress-inducedPromotes
USP1KnockdownLung fibroblast, Foreskin fibroblastWI-38, BJNoOncogene-inducedInhibits
VEGFAOverexpressionDermal endothelialPrimary cellNoReplicativeInhibits
VENTXOverexpression, KnockdownEmbryonic kidney, Osteosarcoma, Lung fibroblast, Cervical cancer, Lymphoblastic leukemiaHEK293T, HeLa, U2OS, Nalm16, IMR-90YesReplicativePromotes
WNT16KnockdownLung fibroblastMRC-5NoReplicativePromotes
WNT2KnockdownLung fibroblastWI-38NoReplicativeInhibits
WRNKnockdownFibroblast, WRN syndrome fibroblastAG00780, AG03141YesOncogene-inducedInhibits
WT1KnockoutLung cancerNCI-H1568, NCI-H23, NCI-H522, NCI-H1437, NCI-H1650, NCI-H1975, NCI-H2126, NCI-H358, NCI-H441, NCI-H460, NCI-H727, NCI-H1299, NCI-H2009, NCI-A549YesOncogene-inducedInhibits
WWP1Overexpression, KnockdownLung fibroblastWI-38, 2BSNoReplicativeInhibits
XAF1Overexpression, KnockdownDermal microvascular endothelial cellsPrimary cellNoStress-inducedPromotes
YAP1KnockdownLung fibroblast, Foreskin fibroblastIMR-90, WI-38, BJNoReplicativeInhibits
YPEL3Knockdown, OverexpressionBreast cancerMCF-7YesStress-inducedPromotes
ZFP36OverexpressionCervical cancerHeLaYesReplicativePromotes
ZMAT3KnockdownDermal fibroblast, Breast cancer, Osteosarcoma, Embryonic kidneyMCF-7, HEK293T, U2OSYesReplicativeInhibits
ZNF148KnockoutLung cancerNCI-H460YesReplicativeInhibits