Cell Senescence-associated Genes

Found 279 results. Showing results 261 to 279.

Show: Sort: First Previous  of 14
Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
TRPM8KnockdownPancreatic cancerBxPC-3, PANC-1YesReplicativeInhibits
TXNKnockdownForeskin fibroblastBJ, BJE-LTNoReplicativeInhibits
TXNIPKnockout, OverexpressionLung fibroblast2BSNoOncogene-induced, ReplicativePromotes
TYK2OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
UBTD1OverexpressionBreast cancer, Colorectal cancer, Gastric cancer, Gastric epithelial, Lung fibroblast, Prostate cancerAGS, GES-1, KATO-III, LoVo, MCF-7, MKN28, MKN45, MRC-5, NCI-N87, PC-3, SGC-7901, SNU-1, SNU-16YesReplicative, Stress-inducedPromotes
USP1KnockdownForeskin fibroblast, Lung fibroblastBJ, WI-38NoOncogene-inducedInhibits
VEGFAOverexpressionDermal endothelialPrimary cellNoReplicativeInhibits
VENTXKnockdown, OverexpressionCervical cancer, Embryonic kidney, Lung fibroblast, Lymphoblastic leukemia, OsteosarcomaHEK293T, HeLa, IMR-90, Nalm16, U2OSYesReplicativePromotes
WNT16KnockdownLung fibroblastMRC-5NoReplicativePromotes
WNT2KnockdownLung fibroblastWI-38NoReplicativeInhibits
WRNKnockdownFibroblast, WRN syndrome fibroblastAG00780, AG03141YesOncogene-inducedInhibits
WT1KnockoutLung cancerNCI-A549, NCI-H1299, NCI-H1437, NCI-H1568, NCI-H1650, NCI-H1975, NCI-H2009, NCI-H2126, NCI-H23, NCI-H358, NCI-H441, NCI-H460, NCI-H522, NCI-H727YesOncogene-inducedInhibits
WWP1Knockdown, OverexpressionLung fibroblast2BS, WI-38NoReplicativeInhibits
XAF1Knockdown, OverexpressionDermal microvascular endothelial cellsPrimary cellNoStress-inducedPromotes
YAP1KnockdownForeskin fibroblast, Lung fibroblastBJ, IMR-90, WI-38NoReplicativeInhibits
YPEL3Knockdown, OverexpressionBreast cancerMCF-7YesStress-inducedPromotes
ZFP36OverexpressionCervical cancerHeLaYesReplicativePromotes
ZMAT3KnockdownBreast cancer, Dermal fibroblast, Embryonic kidney, OsteosarcomaHEK293T, MCF-7, U2OSYesReplicativeInhibits
ZNF148KnockoutLung cancerNCI-H460YesReplicativeInhibits