Cell Senescence-associated Genes

Found 279 results. Showing results 241 to 260.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
STK40OverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
SUPT5HKnockoutCervical cancerHeLaYesOncogene-inducedInhibits
SYKOverexpressionMelanomaA375, SK-MEL-28, 501-melYesReplicativePromotes
TACC3KnockoutBreast cancerMCF-7YesStress-inducedInhibits
TBX2KnockdownMelanomaB16YesReplicativeInhibits
TERCKnockdownCervical cancerHeLaYesReplicativeInhibits
TERF2KnockoutNeuroblastomaSH-SY5YYesReplicativeInhibits
TERTOverexpressionForeskin fibroblast, Retinal pigment epithelialRPE-340, BJNoReplicativeInhibits
TFAP4OverexpressionRetinal pigment epithelial, Breast cancerhTERT-RPE, MCF-7YesReplicativePromotes
TFDP1KnockdownLung cancer, Cervical cancer, Lung fibroblastHeLa, A549, WI-38YesReplicativeInhibits
TGFB1I1Knockout, OverexpressionFibroblastKMST-6, SUSM-1NoReplicativePromotes
TLR3OverexpressionFibroblast, KeratinocytePrimary cellNoReplicativePromotes
TMSB4XOverexpressionNucleus pulposusPrimary cellNoReplicativeInhibits
TNFSF13KnockdownColon cancerSW480YesReplicativeInhibits
TNFSF15Overexpression, KnockoutEndothelial progenitorPrimary cellNoReplicativePromotes
TOP1KnockoutLung fibroblastWI-38, IMR-90NoReplicativePromotes
TP53OverexpressionBladder cancerEJYesStress-induced, ReplicativePromotes
TP63KnockoutForeskin fibroblastBJNoReplicativePromotes
TPRKnockdownCervical cancer, Melanoma, OsteosarcomaHeLa, U2OS, A375YesReplicativeInhibits
TRIM28KnockoutLung fibroblastIMR-90NoOncogene-inducedPromotes