Cell Senescence-associated Genes

Found 279 results. Showing results 241 to 260.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
STK40OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
SUPT5HKnockoutCervical cancerHeLaYesOncogene-inducedInhibits
SYKOverexpressionMelanoma501-mel, A375, SK-MEL-28YesReplicativePromotes
TACC3KnockoutBreast cancerMCF-7YesStress-inducedInhibits
TBX2KnockdownMelanomaB16YesReplicativeInhibits
TERCKnockdownCervical cancerHeLaYesReplicativeInhibits
TERF2KnockoutNeuroblastomaSH-SY5YYesReplicativeInhibits
TERTOverexpressionForeskin fibroblast, Retinal pigment epithelialBJ, RPE-340NoReplicativeInhibits
TFAP4OverexpressionBreast cancer, Retinal pigment epithelialhTERT-RPE, MCF-7YesReplicativePromotes
TFDP1KnockdownCervical cancer, Lung cancer, Lung fibroblastA549, HeLa, WI-38YesReplicativeInhibits
TGFB1I1Knockout, OverexpressionFibroblastKMST-6, SUSM-1NoReplicativePromotes
TLR3OverexpressionFibroblast, KeratinocytePrimary cellNoReplicativePromotes
TMSB4XOverexpressionNucleus pulposusPrimary cellNoReplicativeInhibits
TNFSF13KnockdownColon cancerSW480YesReplicativeInhibits
TNFSF15Knockout, OverexpressionEndothelial progenitorPrimary cellNoReplicativePromotes
TOP1KnockoutLung fibroblastIMR-90, WI-38NoReplicativePromotes
TP53OverexpressionBladder cancerEJYesReplicative, Stress-inducedPromotes
TP63KnockoutForeskin fibroblastBJNoReplicativePromotes
TPRKnockdownCervical cancer, Melanoma, OsteosarcomaA375, HeLa, U2OSYesReplicativeInhibits
TRIM28KnockoutLung fibroblastIMR-90NoOncogene-inducedPromotes