Cell Senescence-associated Genes

Found 34 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AKR1B1Knockdown, OverexpressionKeratinocyteHaCatYesStress-inducedInhibits
ATF7IPKnockdownLung fibroblastIMR-90NoStress-inducedInhibits
BHLHE40OverexpressionBreast cancer, Esophageal cancerEC9706, MCF-7YesReplicative, Stress-inducedPromotes
BLVRAKnockdownFibroblastPrimary cellNoStress-inducedInhibits
BRCA1MutationBreast cancerHBL100, HCC1937, MCF-7YesStress-inducedInhibits
CEBPBKnockdown, OverexpressionProstate cancerLNCaPYesStress-inducedPromotes
CHEK1KnockoutColon cancerHCT116YesStress-inducedPromotes
EZH2KnockdownGastric cancerSGC-7901YesStress-inducedInhibits
GATA4Knockdown, OverexpressionForeskin fibroblast, Lung fibroblastBJ, IMR-90NoReplicative, Stress-inducedPromotes
HSPA5Knockout, OverexpressionOvarian cancerA2780YesStress-inducedInhibits
HSPB2Knockdown, OverexpressionBreast epithelialMCF-10A, MCF-7NoStress-inducedInhibits
ID4OverexpressionProstate cancerDU145YesStress-inducedPromotes
IGFBP3KnockdownLung fibroblastWI-38NoStress-inducedPromotes
ITSN2Knockdown, OverexpressionForeskin fibroblast, Lung fibroblastHs68, WI-38NoStress-inducedPromotes
KCNJ12KnockoutBreast cancer, Gastric cancer, Prostate cancerDU145, LNCaP, MCF-7, MKN74, PC-3, SK-BR3, SNU-484, SNU-638, SNU-668, T47DYesStress-inducedInhibits
LIMA1KnockdownLung fibroblastIMR-90NoReplicative, Stress-inducedInhibits
MAGOHKnockdownLung fibroblastIMR-90NoReplicative, Stress-inducedInhibits
MAGOHBKnockdownLung fibroblastIMR-90NoReplicative, Stress-inducedInhibits
MAPK14KnockoutLung fibroblastMRC-5, WI-38NoReplicative, Stress-inducedPromotes
MCL1Knockdown, OverexpressionColon cancerHCT116YesStress-inducedInhibits