Cell Senescence-associated Genes

Found 34 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AKR1B1Overexpression, KnockdownKeratinocyteHaCatYesStress-inducedInhibits
ATF7IPKnockdownLung fibroblastIMR-90NoStress-inducedInhibits
BHLHE40OverexpressionEsophageal cancer, Breast cancerEC9706, MCF-7YesStress-induced, ReplicativePromotes
BLVRAKnockdownFibroblastPrimary cellNoStress-inducedInhibits
BRCA1MutationBreast cancerHBL100, MCF-7, HCC1937YesStress-inducedInhibits
CEBPBOverexpression, KnockdownProstate cancerLNCaPYesStress-inducedPromotes
CHEK1KnockoutColon cancerHCT116YesStress-inducedPromotes
EZH2KnockdownGastric cancerSGC-7901YesStress-inducedInhibits
GATA4Overexpression, KnockdownForeskin fibroblast, Lung fibroblastIMR-90, BJNoReplicative, Stress-inducedPromotes
HSPA5Overexpression, KnockoutOvarian cancerA2780YesStress-inducedInhibits
HSPB2Knockdown, OverexpressionBreast epithelialMCF-10A, MCF-7NoStress-inducedInhibits
ID4OverexpressionProstate cancerDU145YesStress-inducedPromotes
IGFBP3KnockdownLung fibroblastWI-38NoStress-inducedPromotes
ITSN2Knockdown, OverexpressionForeskin fibroblast, Lung fibroblastHs68, WI-38NoStress-inducedPromotes
KCNJ12KnockoutProstate cancer, Breast cancer, Gastric cancerPC-3, DU145, LNCaP, MKN74, SNU-484, SNU-638, SNU-668, MCF-7, SK-BR3, T47DYesStress-inducedInhibits
LIMA1KnockdownLung fibroblastIMR-90NoStress-induced, ReplicativeInhibits
MAGOHKnockdownLung fibroblastIMR-90NoStress-induced, ReplicativeInhibits
MAGOHBKnockdownLung fibroblastIMR-90NoReplicative, Stress-inducedInhibits
MAPK14KnockoutLung fibroblastWI-38, MRC-5NoStress-induced, ReplicativePromotes
MCL1Overexpression, KnockdownColon cancerHCT116YesStress-inducedInhibits