Cell Senescence-associated Genes

Found 165 results. Showing results 1 to 20.

Show: Sort: of 9 Next Last 
Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AAK1OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativeInduces
ABI3OverexpressionColon cancer, Thyroid cancerARO, WROYesReplicativeInduces
ADCK5OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativeInduces
AGTKnockout, OverexpressionVascular smooth musclePrimary cellNoReplicativeInduces
AKR1B1Knockdown, OverexpressionKeratinocyteHaCatYesStress-inducedInhibits
AKT1OverexpressionAortic endothelial, Dermal microvascular endothelial cells, Umbilical vein endothelialPrimary cellNoOncogene-inducedInduces
ALOX15BOverexpressionProstate epithelialPrimary cellNoReplicativeInduces
ARKnockdown, OverexpressionHair follicular keratinocytePrimary cellNoReplicativeInduces
ARPC1BOverexpressionOsteosarcomaSaOs-2YesReplicativeInduces
ASF1AKnockout, OverexpressionLung fibroblastPrimary cellNoOncogene-induced, ReplicativeInduces
AXLOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativeInduces
BCL6OverexpressionB-cellPrimary cellNoReplicativeInhibits
BHLHE40OverexpressionBreast cancer, Esophageal cancerEC9706, MCF-7YesReplicative, Stress-inducedInduces
BLKOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativeInduces
BMI1Knockout, OverexpressionForeskin fibroblast, Lung fibroblast, Skin fibroblast82-6, BJ, WI-38NoReplicativeInhibits
BRAFOverexpressionForeskin fibroblast, MelanocyteBJ, Primary cellNoOncogene-inducedInduces
CBX7Knockdown, OverexpressionKeratinocyte, Lung fibroblastPrimary cell, WI-38NoReplicativeInhibits
CBX8OverexpressionFibroblastTIG-3NoReplicativeInhibits
CCND1OverexpressionFibroblastHs68, WI-38NoReplicativeInduces
CDK18OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativeInduces