Cell Senescence-associated Genes

Found 165 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AAK1OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
ABI3OverexpressionColon cancer, Thyroid cancerARO, WROYesReplicativePromotes
ADCK5OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
AGTKnockout, OverexpressionVascular smooth musclePrimary cellNoReplicativePromotes
AKR1B1Knockdown, OverexpressionKeratinocyteHaCatYesStress-inducedInhibits
AKT1OverexpressionAortic endothelial, Dermal microvascular endothelial cells, Umbilical vein endothelialPrimary cellNoOncogene-inducedPromotes
ALOX15BOverexpressionProstate epithelialPrimary cellNoReplicativePromotes
ARKnockdown, OverexpressionHair follicular keratinocytePrimary cellNoReplicativePromotes
ARPC1BOverexpressionOsteosarcomaSaOs-2YesReplicativePromotes
ASF1AKnockout, OverexpressionLung fibroblastPrimary cellNoOncogene-induced, ReplicativePromotes
AXLOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
BCL6OverexpressionB-cellPrimary cellNoReplicativeInhibits
BHLHE40OverexpressionBreast cancer, Esophageal cancerEC9706, MCF-7YesReplicative, Stress-inducedPromotes
BLKOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
BMI1Knockout, OverexpressionForeskin fibroblast, Lung fibroblast, Skin fibroblast82-6, BJ, WI-38NoReplicativeInhibits
BRAFOverexpressionForeskin fibroblast, MelanocyteBJ, Primary cellNoOncogene-inducedPromotes
CBX7Knockdown, OverexpressionKeratinocyte, Lung fibroblastPrimary cell, WI-38NoReplicativeInhibits
CBX8OverexpressionFibroblastTIG-3NoReplicativeInhibits
CCND1OverexpressionFibroblastHs68, WI-38NoReplicativePromotes
CDK18OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes