Cell Senescence-associated Genes

Found 14 results. Showing results 1 to 14.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AURKAKnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
CDK1KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
CSNK1A1KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
EPHA3KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
KSR2KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeUnclear
LATS1KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
MAP2K3KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
MAP4K1KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
MYLKKnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
NEK1KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
PIK3C2AKnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeUnclear
SMG1KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
TERTOverexpressionForeskin fibroblast, Retinal pigment epithelialBJ, RPE-340NoReplicativeInhibits
TFAP4OverexpressionBreast cancer, Retinal pigment epithelialhTERT-RPE, MCF-7YesReplicativePromotes