Cell Senescence-associated Genes

Found 8 results. Showing results 1 to 8.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
HMGB1KnockdownMelanoma, Lung cancerA375, G361, SK-MEL-28, NCI-H1299YesReplicativeInhibits
NOTCH3KnockdownGlioma, Fibroblast, Melanoma, Foreskin fibroblast, Breast cancerBJ, LF1, WS1, MDA-MB-231, A375P, T98GYesStress-inducedPromotes
PNPT1OverexpressionMelanomaHO-1, FO-1, MeWoYesReplicativePromotes
PSMD14KnockdownColorectal cancer, Melanoma, Pancreatic cancer, Lung cancer, Breast cancer, Cervical cancer, Prostate cancer, Ovarian cancer, GliomaDU145, NCI-H460, HCT116, HeLa, Mia PaCa-2, SNB-75, NCI-H1299, NCI-H23, NCI-H522, SK-LU-1, A427, A549, SK-BR-3, SK-MEL-2, HCC1937, BTS49-SK-OV-3YesReplicativeInhibits
SFNOverexpressionMelanomaSK-MEL-19, SK-MEL-29, SK-MEL-147YesOncogene-inducedPromotes
SYKOverexpressionMelanomaA375, SK-MEL-28, 501-melYesReplicativePromotes
TBX2KnockdownMelanomaB16YesReplicativeInhibits
TPRKnockdownCervical cancer, Melanoma, OsteosarcomaHeLa, U2OS, A375YesReplicativeInhibits