Cell Senescence-associated Genes

Found 8 results. Showing results 1 to 8.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
HMGB1KnockdownLung cancer, MelanomaA375, G361, NCI-H1299, SK-MEL-28YesReplicativeInhibits
NOTCH3KnockdownBreast cancer, Fibroblast, Foreskin fibroblast, Glioma, MelanomaA375P, BJ, LF1, MDA-MB-231, T98G, WS1YesStress-inducedPromotes
PNPT1OverexpressionMelanomaFO-1, HO-1, MeWoYesReplicativePromotes
PSMD14KnockdownBreast cancer, Cervical cancer, Colorectal cancer, Glioma, Lung cancer, Melanoma, Ovarian cancer, Pancreatic cancer, Prostate cancerA427, A549, BTS49-SK-OV-3, DU145, HCC1937, HCT116, HeLa, Mia PaCa-2, NCI-H1299, NCI-H23, NCI-H460, NCI-H522, SK-BR-3, SK-LU-1, SK-MEL-2, SNB-75YesReplicativeInhibits
SFNOverexpressionMelanomaSK-MEL-147, SK-MEL-19, SK-MEL-29YesOncogene-inducedPromotes
SYKOverexpressionMelanoma501-mel, A375, SK-MEL-28YesReplicativePromotes
TBX2KnockdownMelanomaB16YesReplicativeInhibits
TPRKnockdownCervical cancer, Melanoma, OsteosarcomaA375, HeLa, U2OSYesReplicativeInhibits