Cell Senescence-associated Genes

Found 118 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AAK1OverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
ADCK5OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
ASF1AKnockout, OverexpressionLung fibroblastPrimary cellNoReplicative, Oncogene-inducedPromotes
ATF7IPKnockdownLung fibroblastIMR-90NoStress-inducedInhibits
ATMKnockoutForeskin fibroblast, Lung fibroblastMRC-5, WI-38, BJNoReplicativeInhibits
AXLOverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
BLKOverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
BMI1Knockout, OverexpressionForeskin fibroblast, Lung fibroblast, Skin fibroblastWI-38, BJ, 82-6NoReplicativeInhibits
BTG3KnockdownLung fibroblastIMR-90, WI-38NoReplicativeInhibits
C11orf31KnockdownLung fibroblastMRC-5NoReplicativeInhibits
CBX7Overexpression, KnockdownLung fibroblast, KeratinocyteWI-38, Primary cellNoReplicativeInhibits
CDK18OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
CDKN1BOverexpressionLung fibroblastTIG-3NoReplicativePromotes
CDKN2AOverexpressionLung fibroblastTIG-3NoReplicativePromotes
CDKN2AIPOverexpressionLung fibroblastTIG-1, MRC-5NoReplicativePromotes
CENPAKnockdownLung fibroblastTIG-3NoReplicativeInhibits
CKBOverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
CPEB1Overexpression, KnockoutLung fibroblast, Foreskin fibroblastPrimary cell, WI-38NoReplicativePromotes
CSNK2A1KnockdownLung fibroblastIMR-90NoReplicativeInhibits
CYR61OverexpressionLung fibroblast, Foreskin fibroblastBJ, IMR-90NoReplicativePromotes