Cell Senescence-associated Genes

Found 11 results. Showing results 1 to 11.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
CTNNAL1KnockdownLung cancer, Squamous carcinomaA549, OC2YesReplicativeInhibits
GAPDHKnockdownLung cancerA549YesReplicativeInhibits
HMGB1KnockdownLung cancer, MelanomaA375, G361, NCI-H1299, SK-MEL-28YesReplicativeInhibits
KDM4AKnockdownLung cancerA549YesReplicativeUnclear
NEK6OverexpressionBladder cancer, Lung cancerEJ, NCI-H1299YesReplicativeInhibits
PEBP1Knockdown, OverexpressionColon cancer, Gastric cancer, Lung cancer, Prostate cancerA549, HCT116, MKN45, PC-3YesStress-inducedPromotes
PSMD14KnockdownBreast cancer, Cervical cancer, Colorectal cancer, Glioma, Lung cancer, Melanoma, Ovarian cancer, Pancreatic cancer, Prostate cancerA427, A549, BTS49-SK-OV-3, DU145, HCC1937, HCT116, HeLa, Mia PaCa-2, NCI-H1299, NCI-H23, NCI-H460, NCI-H522, SK-BR-3, SK-LU-1, SK-MEL-2, SNB-75YesReplicativeInhibits
RBX1KnockdownGlioblastoma, Lung cancerU87YesReplicativeInhibits
TFDP1KnockdownCervical cancer, Lung cancer, Lung fibroblastA549, HeLa, WI-38YesReplicativeInhibits
WT1KnockoutLung cancerNCI-A549, NCI-H1299, NCI-H1437, NCI-H1568, NCI-H1650, NCI-H1975, NCI-H2009, NCI-H2126, NCI-H23, NCI-H358, NCI-H441, NCI-H460, NCI-H522, NCI-H727YesOncogene-inducedInhibits
ZNF148KnockoutLung cancerNCI-H460YesReplicativeInhibits