Cell Senescence-associated Genes

Found 40 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
ATMKnockoutForeskin fibroblast, Lung fibroblastBJ, MRC-5, WI-38NoReplicativeInhibits
BMI1Knockout, OverexpressionForeskin fibroblast, Lung fibroblast, Skin fibroblast82-6, BJ, WI-38NoReplicativeInhibits
BRAFOverexpressionForeskin fibroblast, MelanocyteBJ, Primary cellNoOncogene-inducedPromotes
BRD7KnockdownForeskin fibroblastBJNoReplicativePromotes
CDK4OverexpressionForeskin fibroblastBJNoReplicativeInhibits
CDK6OverexpressionForeskin fibroblastBJNoReplicativeInhibits
CPEB1Knockout, OverexpressionForeskin fibroblast, Lung fibroblastPrimary cell, WI-38NoReplicativePromotes
CYR61OverexpressionForeskin fibroblast, Lung fibroblastBJ, IMR-90NoReplicativePromotes
DLX2OverexpressionForeskin fibroblast, Lung fibroblastBJ, IMR-90NoReplicativeInhibits
ETS1OverexpressionForeskin fibroblast, Lung fibroblastHs68, TIG-3NoOncogene-inducedPromotes
ETS2OverexpressionForeskin fibroblast, Lung fibroblastHs68, TIG-3NoOncogene-inducedPromotes
G6PDKnockoutForeskin fibroblastPrimary cellNoReplicativeInhibits
GATA4Knockdown, OverexpressionForeskin fibroblast, Lung fibroblastBJ, IMR-90NoReplicative, Stress-inducedPromotes
GLB1KnockdownForeskin fibroblastPrimary cellNoReplicativeInhibits
HIVEP1KnockdownForeskin fibroblastPrimary cellNoReplicativeInhibits
IL8OverexpressionForeskin fibroblast, Lung fibroblastBJ, IMR-90, WI-38NoReplicativePromotes
ING1OverexpressionForeskin fibroblastHs68NoReplicativePromotes
IRF3OverexpressionForeskin fibroblastBJNoReplicativePromotes
ITSN2Knockdown, OverexpressionForeskin fibroblast, Lung fibroblastHs68, WI-38NoStress-inducedPromotes
MAGEA2OverexpressionForeskin fibroblastBJNoOncogene-inducedInhibits