Cell Senescence-associated Genes

Found 40 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
ATMKnockoutForeskin fibroblast, Lung fibroblastBJ, MRC-5, WI-38NoReplicativeInhibits
BMI1Knockout, OverexpressionForeskin fibroblast, Lung fibroblast, Skin fibroblast82-6, BJ, WI-38NoReplicativeInhibits
BRAFOverexpressionForeskin fibroblast, MelanocyteBJ, Primary cellNoOncogene-inducedInduces
BRD7KnockdownForeskin fibroblastBJNoReplicativeInduces
CDK4OverexpressionForeskin fibroblastBJNoReplicativeInhibits
CDK6OverexpressionForeskin fibroblastBJNoReplicativeInhibits
CPEB1Knockout, OverexpressionForeskin fibroblast, Lung fibroblastPrimary cell, WI-38NoReplicativeInduces
CYR61OverexpressionForeskin fibroblast, Lung fibroblastBJ, IMR-90NoReplicativeInduces
DLX2OverexpressionForeskin fibroblast, Lung fibroblastBJ, IMR-90NoReplicativeInhibits
ETS1OverexpressionForeskin fibroblast, Lung fibroblastHs68, TIG-3NoOncogene-inducedInduces
ETS2OverexpressionForeskin fibroblast, Lung fibroblastHs68, TIG-3NoOncogene-inducedInduces
G6PDKnockoutForeskin fibroblastPrimary cellNoReplicativeInhibits
GATA4Knockdown, OverexpressionForeskin fibroblast, Lung fibroblastBJ, IMR-90NoReplicative, Stress-inducedInduces
GLB1KnockdownForeskin fibroblastPrimary cellNoReplicativeInhibits
HIVEP1KnockdownForeskin fibroblastPrimary cellNoReplicativeInhibits
IL8OverexpressionForeskin fibroblast, Lung fibroblastBJ, IMR-90, WI-38NoReplicativeInduces
ING1OverexpressionForeskin fibroblastHs68NoReplicativeInduces
IRF3OverexpressionForeskin fibroblastBJNoReplicativeInduces
ITSN2Knockdown, OverexpressionForeskin fibroblast, Lung fibroblastHs68, WI-38NoStress-inducedInduces
MAGEA2OverexpressionForeskin fibroblastBJNoOncogene-inducedInhibits