Cell Senescence-associated Genes

Found 40 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
ATMKnockoutForeskin fibroblast, Lung fibroblastMRC-5, WI-38, BJNoReplicativeInhibits
BMI1Knockout, OverexpressionForeskin fibroblast, Lung fibroblast, Skin fibroblastWI-38, BJ, 82-6NoReplicativeInhibits
BRAFOverexpressionForeskin fibroblast, MelanocytePrimary cell, BJNoOncogene-inducedPromotes
BRD7KnockdownForeskin fibroblastBJNoReplicativePromotes
CDK4OverexpressionForeskin fibroblastBJNoReplicativeInhibits
CDK6OverexpressionForeskin fibroblastBJNoReplicativeInhibits
CPEB1Overexpression, KnockoutLung fibroblast, Foreskin fibroblastPrimary cell, WI-38NoReplicativePromotes
CYR61OverexpressionLung fibroblast, Foreskin fibroblastBJ, IMR-90NoReplicativePromotes
DLX2OverexpressionForeskin fibroblast, Lung fibroblastBJ, IMR-90NoReplicativeInhibits
ETS1OverexpressionLung fibroblast, Foreskin fibroblastTIG-3, Hs68NoOncogene-inducedPromotes
ETS2OverexpressionForeskin fibroblast, Lung fibroblastTIG-3, Hs68NoOncogene-inducedPromotes
G6PDKnockoutForeskin fibroblastPrimary cellNoReplicativeInhibits
GATA4Overexpression, KnockdownForeskin fibroblast, Lung fibroblastIMR-90, BJNoReplicative, Stress-inducedPromotes
GLB1KnockdownForeskin fibroblastPrimary cellNoReplicativeInhibits
HIVEP1KnockdownForeskin fibroblastPrimary cellNoReplicativeInhibits
IL8OverexpressionForeskin fibroblast, Lung fibroblastIMR-90, BJ, WI-38NoReplicativePromotes
ING1OverexpressionForeskin fibroblastHs68NoReplicativePromotes
IRF3OverexpressionForeskin fibroblastBJNoReplicativePromotes
ITSN2Knockdown, OverexpressionForeskin fibroblast, Lung fibroblastHs68, WI-38NoStress-inducedPromotes
MAGEA2OverexpressionForeskin fibroblastBJNoOncogene-inducedInhibits