Cell Senescence-associated Genes

Found 163 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AAK1OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativeInduces
ACLYKnockoutDermal fibroblastPrimary cellNoReplicativeInhibits
ADCK5OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativeInduces
ASF1AKnockout, OverexpressionLung fibroblastPrimary cellNoOncogene-induced, ReplicativeInduces
ATF7IPKnockdownLung fibroblastIMR-90NoStress-inducedInhibits
ATMKnockoutForeskin fibroblast, Lung fibroblastBJ, MRC-5, WI-38NoReplicativeInhibits
AXLOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativeInduces
BLKOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativeInduces
BLVRAKnockdownFibroblastPrimary cellNoStress-inducedInhibits
BMI1Knockout, OverexpressionForeskin fibroblast, Lung fibroblast, Skin fibroblast82-6, BJ, WI-38NoReplicativeInhibits
BRAFOverexpressionForeskin fibroblast, MelanocyteBJ, Primary cellNoOncogene-inducedInduces
BRD7KnockdownForeskin fibroblastBJNoReplicativeInduces
BTG3KnockdownLung fibroblastIMR-90, WI-38NoReplicativeInhibits
C11orf31KnockdownLung fibroblastMRC-5NoReplicativeInhibits
CAV1KnockdownFibroblastPrimary cellNoReplicativeInduces
CBX7Knockdown, OverexpressionKeratinocyte, Lung fibroblastPrimary cell, WI-38NoReplicativeInhibits
CBX8OverexpressionFibroblastTIG-3NoReplicativeInhibits
CCND1OverexpressionFibroblastHs68, WI-38NoReplicativeInduces
CDK18OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativeInduces
CDK2AP1KnockdownDermal fibroblastPrimary cellNoReplicativeInhibits