Cell Senescence-associated Genes

Found 163 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AAK1OverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
ACLYKnockoutDermal fibroblastPrimary cellNoReplicativeInhibits
ADCK5OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
ASF1AKnockout, OverexpressionLung fibroblastPrimary cellNoReplicative, Oncogene-inducedPromotes
ATF7IPKnockdownLung fibroblastIMR-90NoStress-inducedInhibits
ATMKnockoutForeskin fibroblast, Lung fibroblastMRC-5, WI-38, BJNoReplicativeInhibits
AXLOverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
BLKOverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
BLVRAKnockdownFibroblastPrimary cellNoStress-inducedInhibits
BMI1Knockout, OverexpressionForeskin fibroblast, Lung fibroblast, Skin fibroblastWI-38, BJ, 82-6NoReplicativeInhibits
BRAFOverexpressionForeskin fibroblast, MelanocytePrimary cell, BJNoOncogene-inducedPromotes
BRD7KnockdownForeskin fibroblastBJNoReplicativePromotes
BTG3KnockdownLung fibroblastIMR-90, WI-38NoReplicativeInhibits
C11orf31KnockdownLung fibroblastMRC-5NoReplicativeInhibits
CAV1KnockdownFibroblastPrimary cellNoReplicativePromotes
CBX7Overexpression, KnockdownLung fibroblast, KeratinocyteWI-38, Primary cellNoReplicativeInhibits
CBX8OverexpressionFibroblastTIG-3NoReplicativeInhibits
CCND1OverexpressionFibroblastWI-38, Hs68NoReplicativePromotes
CDK18OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
CDK2AP1KnockdownDermal fibroblastPrimary cellNoReplicativeInhibits