Cell Senescence-associated Genes

Found 47 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AAK1OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
ADCK5OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
AURKAKnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
AXLOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
BLKOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
CDK1KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
CDK18OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
CKBOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
CSNK1A1KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
DUSP16KnockdownEmbryonic kidney, Liver cancerHEK293FT, HepG2, PLC/PRF/5YesReplicativeInhibits
EPHA3KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
FASTKOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
GRK6OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
HK3OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
ITPK1OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
ITPKBOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
KSR2KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeUnclear
LATS1KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
LIMK1OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
MAP2K3KnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits