Cell Senescence-associated Genes

Found 47 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AAK1OverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
ADCK5OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
AURKAKnockdownEmbryonic kidney, Retinal pigment epithelialhTERT-RPE1, HEK293TYesReplicativeInhibits
AXLOverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
BLKOverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
CDK1KnockdownRetinal pigment epithelial, Embryonic kidneyhTERT-RPE1, HEK293TYesReplicativeInhibits
CDK18OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
CKBOverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
CSNK1A1KnockdownEmbryonic kidney, Retinal pigment epithelialhTERT-RPE1, HEK293TYesReplicativeInhibits
DUSP16KnockdownEmbryonic kidney, Liver cancerHepG2, PLC/PRF/5, HEK293FTYesReplicativeInhibits
EPHA3KnockdownRetinal pigment epithelial, Embryonic kidneyhTERT-RPE1, HEK293TYesReplicativeInhibits
FASTKOverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
GRK6OverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
HK3OverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
ITPK1OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
ITPKBOverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
KSR2KnockdownEmbryonic kidney, Retinal pigment epithelialhTERT-RPE1, HEK293TYesReplicativeUnclear
LATS1KnockdownEmbryonic kidney, Retinal pigment epithelialhTERT-RPE1, HEK293TYesReplicativeInhibits
LIMK1OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
MAP2K3KnockdownRetinal pigment epithelial, Embryonic kidneyhTERT-RPE1, HEK293TYesReplicativeInhibits