Cell Senescence-associated Genes

Found 9 results. Showing results 1 to 9.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
ABI3OverexpressionThyroid cancer, Colon cancerWRO, AROYesReplicativePromotes
CHEK1KnockoutColon cancerHCT116YesStress-inducedPromotes
KDM5BKnockdownColon cancerHCT116, DLD1, Colo201YesReplicativeInhibits
MCL1Overexpression, KnockdownColon cancerHCT116YesStress-inducedInhibits
PEBP1Overexpression, KnockdownProstate cancer, Colon cancer, Lung cancer, Gastric cancerA549, MKN45, PC-3, HCT116YesStress-inducedPromotes
RPS6KA6Knockdown, OverexpressionColon cancer, Lung fibroblastIMR-90NoReplicativePromotes
SLC16A7KnockdownGastric cancer, Colon cancerLoVo, HT29, HCT8, HCT116, SW480, DLD1, MKN45, MKN74YesReplicativeInhibits
SOX2OverexpressionColon cancer, Embryonic kidneyHEK293T, HCT116, WiDrYesReplicativePromotes
TNFSF13KnockdownColon cancerSW480YesReplicativeInhibits