Cell Senescence-associated Genes

Found 9 results. Showing results 1 to 9.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
ABI3OverexpressionColon cancer, Thyroid cancerARO, WROYesReplicativePromotes
CHEK1KnockoutColon cancerHCT116YesStress-inducedPromotes
KDM5BKnockdownColon cancerColo201, DLD1, HCT116YesReplicativeInhibits
MCL1Knockdown, OverexpressionColon cancerHCT116YesStress-inducedInhibits
PEBP1Knockdown, OverexpressionColon cancer, Gastric cancer, Lung cancer, Prostate cancerA549, HCT116, MKN45, PC-3YesStress-inducedPromotes
RPS6KA6Knockdown, OverexpressionColon cancer, Lung fibroblastIMR-90NoReplicativePromotes
SLC16A7KnockdownColon cancer, Gastric cancerDLD1, HCT116, HCT8, HT29, LoVo, MKN45, MKN74, SW480YesReplicativeInhibits
SOX2OverexpressionColon cancer, Embryonic kidneyHCT116, HEK293T, WiDrYesReplicativePromotes
TNFSF13KnockdownColon cancerSW480YesReplicativeInhibits