Cell Senescence-associated Genes

Found 13 results. Showing results 1 to 13.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
DUSP3KnockdownCervical cancerHeLaYesReplicativeInhibits
HDAC1OverexpressionCervical cancerHeLaYesReplicativePromotes
MARCH5KnockdownCervical cancerHeLayesReplicativeInhibits
PSMD14KnockdownColorectal cancer, Melanoma, Pancreatic cancer, Lung cancer, Breast cancer, Cervical cancer, Prostate cancer, Ovarian cancer, GliomaDU145, NCI-H460, HCT116, HeLa, Mia PaCa-2, SNB-75, NCI-H1299, NCI-H23, NCI-H522, SK-LU-1, A427, A549, SK-BR-3, SK-MEL-2, HCC1937, BTS49-SK-OV-3YesReplicativeInhibits
PTRFOverexpression, KnockdownLung fibroblast, Cervical cancerWI-38, IMR-90, HeLaNoReplicativePromotes
RBP2KnockoutCervical cancer, Gastric cancerAGS, BGC-823, HGC-27, KATO-III, HeLa, SiHaYesReplicativeInhibits
SPIN1OverexpressionCervical cancerHeLaYesReplicativePromotes
SUPT5HKnockoutCervical cancerHeLaYesOncogene-inducedInhibits
TERCKnockdownCervical cancerHeLaYesReplicativeInhibits
TFDP1KnockdownLung cancer, Cervical cancer, Lung fibroblastHeLa, A549, WI-38YesReplicativeInhibits
TPRKnockdownCervical cancer, Melanoma, OsteosarcomaHeLa, U2OS, A375YesReplicativeInhibits
VENTXOverexpression, KnockdownEmbryonic kidney, Osteosarcoma, Lung fibroblast, Cervical cancer, Lymphoblastic leukemiaHEK293T, HeLa, U2OS, Nalm16, IMR-90YesReplicativePromotes
ZFP36OverexpressionCervical cancerHeLaYesReplicativePromotes