Cell Senescence-associated Genes

Found 17 results. Showing results 1 to 17.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
BHLHE40OverexpressionBreast cancer, Esophageal cancerEC9706, MCF-7YesReplicative, Stress-inducedPromotes
BRCA1MutationBreast cancerHBL100, HCC1937, MCF-7YesStress-inducedInhibits
FBXO31OverexpressionBreast cancerMCF-7YesReplicativePromotes
HEPACAMOverexpressionBreast cancerMCF-7YesReplicativePromotes
IGFBP1OverexpressionBreast cancerMCF-7YesReplicativePromotes
KCNJ12KnockoutBreast cancer, Gastric cancer, Prostate cancerDU145, LNCaP, MCF-7, MKN74, PC-3, SK-BR3, SNU-484, SNU-638, SNU-668, T47DYesStress-inducedInhibits
NOTCH3KnockdownBreast cancer, Fibroblast, Foreskin fibroblast, Glioma, MelanomaA375P, BJ, LF1, MDA-MB-231, T98G, WS1YesStress-inducedPromotes
PDZD2OverexpressionBreast cancer, Liver cancer, Prostate cancerDU145YesReplicativePromotes
PRKCHKnockdown, OverexpressionBreast cancerMCF-7YesStress-inducedPromotes
PRMT6KnockdownBreast cancer, Breast epithelialMCF-10A, MCF-7, MDA-MB-231, MDA-MB-468, SK-BR-3YesReplicativeInhibits
PSMD14KnockdownBreast cancer, Cervical cancer, Colorectal cancer, Glioma, Lung cancer, Melanoma, Ovarian cancer, Pancreatic cancer, Prostate cancerA427, A549, BTS49-SK-OV-3, DU145, HCC1937, HCT116, HeLa, Mia PaCa-2, NCI-H1299, NCI-H23, NCI-H460, NCI-H522, SK-BR-3, SK-LU-1, SK-MEL-2, SNB-75YesReplicativeInhibits
RAD21KnockdownBreast cancerMDA-MB-231NoReplicativeInhibits
TACC3KnockoutBreast cancerMCF-7YesStress-inducedInhibits
TFAP4OverexpressionBreast cancer, Retinal pigment epithelialhTERT-RPE, MCF-7YesReplicativePromotes
UBTD1OverexpressionBreast cancer, Colorectal cancer, Gastric cancer, Gastric epithelial, Lung fibroblast, Prostate cancerAGS, GES-1, KATO-III, LoVo, MCF-7, MKN28, MKN45, MRC-5, NCI-N87, PC-3, SGC-7901, SNU-1, SNU-16YesReplicative, Stress-inducedPromotes
YPEL3Knockdown, OverexpressionBreast cancerMCF-7YesStress-inducedPromotes
ZMAT3KnockdownBreast cancer, Dermal fibroblast, Embryonic kidney, OsteosarcomaHEK293T, MCF-7, U2OSYesReplicativeInhibits