Cell Senescence-associated Genes

Found 17 results. Showing results 1 to 17.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
BHLHE40OverexpressionEsophageal cancer, Breast cancerEC9706, MCF-7YesStress-induced, ReplicativePromotes
BRCA1MutationBreast cancerHBL100, MCF-7, HCC1937YesStress-inducedInhibits
FBXO31OverexpressionBreast cancerMCF-7YesReplicativePromotes
HEPACAMOverexpressionBreast cancerMCF-7YesReplicativePromotes
IGFBP1OverexpressionBreast cancerMCF-7YesReplicativePromotes
KCNJ12KnockoutProstate cancer, Breast cancer, Gastric cancerPC-3, DU145, LNCaP, MKN74, SNU-484, SNU-638, SNU-668, MCF-7, SK-BR3, T47DYesStress-inducedInhibits
NOTCH3KnockdownGlioma, Fibroblast, Melanoma, Foreskin fibroblast, Breast cancerBJ, LF1, WS1, MDA-MB-231, A375P, T98GYesStress-inducedPromotes
PDZD2OverexpressionBreast cancer, Prostate cancer, Liver cancerDU145YesReplicativePromotes
PRKCHOverexpression, KnockdownBreast cancerMCF-7YesStress-inducedPromotes
PRMT6KnockdownBreast cancer, Breast epithelialMCF-7, MDA-MB-231, MDA-MB-468, SK-BR-3, MCF-10AYesReplicativeInhibits
PSMD14KnockdownColorectal cancer, Melanoma, Pancreatic cancer, Lung cancer, Breast cancer, Cervical cancer, Prostate cancer, Ovarian cancer, GliomaDU145, NCI-H460, HCT116, HeLa, Mia PaCa-2, SNB-75, NCI-H1299, NCI-H23, NCI-H522, SK-LU-1, A427, A549, SK-BR-3, SK-MEL-2, HCC1937, BTS49-SK-OV-3YesReplicativeInhibits
RAD21KnockdownBreast cancerMDA-MB-231NoReplicativeInhibits
TACC3KnockoutBreast cancerMCF-7YesStress-inducedInhibits
TFAP4OverexpressionRetinal pigment epithelial, Breast cancerhTERT-RPE, MCF-7YesReplicativePromotes
UBTD1OverexpressionProstate cancer, Gastric cancer, Colorectal cancer, Gastric epithelial, Lung fibroblast, Breast cancerGES-1, MKN28, KATO-III, SNU-1, SNU-16, MKN45, NCI-N87, SGC-7901, AGS, MCF-7, LoVo, PC-3, MRC-5YesReplicative, Stress-inducedPromotes
YPEL3Knockdown, OverexpressionBreast cancerMCF-7YesStress-inducedPromotes
ZMAT3KnockdownDermal fibroblast, Breast cancer, Osteosarcoma, Embryonic kidneyMCF-7, HEK293T, U2OSYesReplicativeInhibits