Cell Senescence-associated Genes

Found 279 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AAK1OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
ABI3OverexpressionColon cancer, Thyroid cancerARO, WROYesReplicativePromotes
ACLYKnockoutDermal fibroblastPrimary cellNoReplicativeInhibits
ADCK5OverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
AGTKnockout, OverexpressionVascular smooth musclePrimary cellNoReplicativePromotes
AKR1B1Knockdown, OverexpressionKeratinocyteHaCatYesStress-inducedInhibits
AKT1OverexpressionAortic endothelial, Dermal microvascular endothelial cells, Umbilical vein endothelialPrimary cellNoOncogene-inducedPromotes
ALOX15BOverexpressionProstate epithelialPrimary cellNoReplicativePromotes
ARKnockdown, OverexpressionHair follicular keratinocytePrimary cellNoReplicativePromotes
ARPC1BOverexpressionOsteosarcomaSaOs-2YesReplicativePromotes
ASF1AKnockout, OverexpressionLung fibroblastPrimary cellNoOncogene-induced, ReplicativePromotes
ASPHKnockdownLiver cancerFOCUS, HepG2, Huh7YesReplicativeInhibits
ATF7IPKnockdownLung fibroblastIMR-90NoStress-inducedInhibits
ATMKnockoutForeskin fibroblast, Lung fibroblastBJ, MRC-5, WI-38NoReplicativeInhibits
AURKAKnockdownEmbryonic kidney, Retinal pigment epithelialHEK293T, hTERT-RPE1YesReplicativeInhibits
AXLOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes
BAG3KnockdownGlioma, Laryngeal cancerA172, HEp2YesReplicativeInhibits
BCL6OverexpressionB-cellPrimary cellNoReplicativeInhibits
BHLHE40OverexpressionBreast cancer, Esophageal cancerEC9706, MCF-7YesReplicative, Stress-inducedPromotes
BLKOverexpressionEmbryonic kidney, Lung fibroblastHEK293T, IMR-90, MRC-5NoReplicativePromotes