Cell Senescence-associated Genes

Found 279 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AAK1OverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
ABI3OverexpressionThyroid cancer, Colon cancerWRO, AROYesReplicativePromotes
ACLYKnockoutDermal fibroblastPrimary cellNoReplicativeInhibits
ADCK5OverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes
AGTOverexpression, KnockoutVascular smooth musclePrimary cellNoReplicativePromotes
AKR1B1Overexpression, KnockdownKeratinocyteHaCatYesStress-inducedInhibits
AKT1OverexpressionAortic endothelial, Umbilical vein endothelial, Dermal microvascular endothelial cellsPrimary cellNoOncogene-inducedPromotes
ALOX15BOverexpressionProstate epithelialPrimary cellNoReplicativePromotes
AROverexpression, KnockdownHair follicular keratinocytePrimary cellNoReplicativePromotes
ARPC1BOverexpressionOsteosarcomaSaOs-2YesReplicativePromotes
ASF1AKnockout, OverexpressionLung fibroblastPrimary cellNoReplicative, Oncogene-inducedPromotes
ASPHKnockdownLiver cancerFOCUS, Huh7, HepG2YesReplicativeInhibits
ATF7IPKnockdownLung fibroblastIMR-90NoStress-inducedInhibits
ATMKnockoutForeskin fibroblast, Lung fibroblastMRC-5, WI-38, BJNoReplicativeInhibits
AURKAKnockdownEmbryonic kidney, Retinal pigment epithelialhTERT-RPE1, HEK293TYesReplicativeInhibits
AXLOverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
BAG3KnockdownLaryngeal cancer, GliomaA172, HEp2YesReplicativeInhibits
BCL6OverexpressionB-cellPrimary cellNoReplicativeInhibits
BHLHE40OverexpressionEsophageal cancer, Breast cancerEC9706, MCF-7YesStress-induced, ReplicativePromotes
BLKOverexpressionEmbryonic kidney, Lung fibroblastIMR-90, MRC-5, HEK293TNoReplicativePromotes