Cell Senescence-associated Genes

Found 279 results. Showing results 1 to 20.

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Gene Name Method Cell Types Cell Lines Cancer Cell Line? Senescence Type Senescence Effect
AAK1OverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
ABI3OverexpressionThyroid cancer, Colon cancerWRO, AROYesReplicativePromotes
ACLYKnockoutDermal fibroblastPrimary cellNoReplicativeInhibits
ADCK5OverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
AGTKnockout, OverexpressionVascular smooth musclePrimary cellNoReplicativePromotes
AKR1B1Knockdown, OverexpressionKeratinocyteHaCatYesStress-inducedInhibits
AKT1OverexpressionUmbilical vein endothelial, Aortic endothelial, Dermal microvascular endothelial cellsPrimary cellNoOncogene-inducedPromotes
ALOX15BOverexpressionProstate epithelialPrimary cellNoReplicativePromotes
ARKnockdown, OverexpressionHair follicular keratinocytePrimary cellNoReplicativePromotes
ARPC1BOverexpressionOsteosarcomaSaOs-2YesReplicativePromotes
ASF1AOverexpression, KnockoutLung fibroblastPrimary cellNoReplicative, Oncogene-inducedPromotes
ASPHKnockdownLiver cancerFOCUS, Huh7, HepG2YesReplicativeInhibits
ATF7IPKnockdownLung fibroblastIMR-90NoStress-inducedInhibits
ATMKnockoutLung fibroblast, Foreskin fibroblastMRC-5, WI-38, BJNoReplicativeInhibits
AURKAKnockdownRetinal pigment epithelial, Embryonic kidneyhTERT-RPE1, HEK293TYesReplicativeInhibits
AXLOverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes
BAG3KnockdownGlioma, Laryngeal cancerA172, HEp2YesReplicativeInhibits
BCL6OverexpressionB-cellPrimary cellNoReplicativeInhibits
BHLHE40OverexpressionEsophageal cancer, Breast cancerEC9706, MCF-7YesReplicative, Stress-inducedPromotes
BLKOverexpressionLung fibroblast, Embryonic kidneyIMR-90, MRC-5, HEK293TNoReplicativePromotes