Cell Senescence Entries for CTNNAL1
- Cell Types
- Lung cancer, Squamous carcinoma
- Cell Lines
- A549, OC2
- Cancer Cell?
- Yes
- Method
- Knockdown
- Type of senescence
- Replicative
- Senescence Effect
- Inhibits
- Observations
- Knockdown of alpha-Catulin (CTNNAL1) in cancer cell lines (OC2 and A549) dramatically decreased cell proliferation and contributed to cellular senescence.
- Primary Reference
CTNNAL1 Gene Information
- HGNC symbol
- CTNNAL1
- Aliases
- ACRP; CLLP; alpha-CATU
- Common name
- catenin alpha like 1
- Entrez Id
- 8727
- Description
CTNNAL1 Ontologies
- Gene Ontology
-
Process: GO:7266; Rho protein signal transduction
GO:7155; cell adhesion
Cellular component: GO:5856; cytoskeleton
GO:5829; cytosol
GO:5886; plasma membrane
Function: GO:51015; actin filament binding
GO:45296; cadherin binding
GO:5515; protein binding
Homologs of CTNNAL1 in Model Organisms
- Caenorhabditis elegans
- ctn-1
- Danio rerio
- ctnnal1
- Drosophila melanogaster
- alpha-catenin-relate
- Mus musculus
- Ctnnal1
- Rattus norvegicus
- Ctnnal1
External links
- OMIM
- 604785
- Ensembl
- ENSG00000119326
- Entrez Gene
- 8727
- UniGene
- 58488
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- CTNNAL1
- GeneCards
- CTNNAL1