Cell Senescence Entries for CSNK1A1
- Cell Types
- Embryonic kidney, Retinal pigment epithelial
- Cell Lines
- HEK293T, HTERT-RPE1
- Cancer Cell?
- Yes
- Method
- Knockdown
- Type of senescence
- Unclear
- Senescence Effect
- Inhibits
- Primary Reference
- Lahtela et al. (2013) A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3. Cell Cycle 12(4)625-34 (PubMed)
CSNK1A1 Gene Information
- HGNC symbol
- CSNK1A1
- Aliases
- CK1; CK1a; CK1alpha; CKIa; CKIalpha
- Common name
- casein kinase 1 alpha 1
- Entrez Id
- 1452
- Description
CSNK1A1 Ontologies
- Gene Ontology
-
Process: GO:6468; protein phosphorylation
GO:7049; cell cycle
GO:16310; phosphorylation
GO:51301; cell division
GO:16055; Wnt signaling pathway
GO:7165; signal transduction
GO:90090; negative regulation of canonical Wnt signaling pathway
GO:18105; peptidyl-serine phosphorylation
GO:7166; cell surface receptor signaling pathway
GO:45104; intermediate filament cytoskeleton organization
GO:7030; Golgi organization
GO:32436; positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:19082; viral protein processing
GO:1904424; regulation of GTP binding
GO:43161; proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:16607; nuclear speck
GO:16020; membrane
GO:5829; cytosol
GO:5856; cytoskeleton
GO:5694; chromosome
GO:42995; cell projection
GO:775; chromosome, centromeric region
GO:5815; microtubule organizing center
GO:5819; spindle
GO:776; kinetochore
GO:5813; centrosome
GO:36064; ciliary basal body
GO:5929; cilium
GO:5847; mRNA cleavage and polyadenylation specificity factor complex
GO:45095; keratin filament
GO:30877; beta-catenin destruction complex
Hide GO termsFunction: GO:166; nucleotide binding
GO:4672; protein kinase activity
GO:4674; protein serine/threonine kinase activity
GO:4712; protein serine/threonine/tyrosine kinase activity
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:106310; protein serine kinase activity
GO:5515; protein binding
Homologs of CSNK1A1 in Model Organisms
- Caenorhabditis elegans
- kin-19
- Danio rerio
- csnk1a1
- Drosophila melanogaster
- CkIalpha
- Drosophila melanogaster
- CG12147
- Drosophila melanogaster
- CG7094
- Drosophila melanogaster
- CG9962
- Saccharomyces cerevisiae
- HRR25
External links
- OMIM
- 600505
- Ensembl
- ENSG00000113712
- Entrez Gene
- 1452
- UniGene
- 712555
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- CSNK1A1
- GeneCards
- CSNK1A1